Real World Evidence

Combining regional health system and policy knowledge with technical and analytic skills to deliver high-impact RWE solutions.

RWE services

Integrated evidence planningReal-world data analysisReal-world evidence generationEvidence synthesis and evaluation

Integrated Evidence Planning (IEP)

CCHO’s holistic, dynamic, and proactive approach encompasses the entire product lifecycle, from clinical development to commercialization and post-marketing activities, integrating RWE and clinical evidence generation and utilization strategies to support your clinical and commercial objectives. We ensure seamless multi-disciplinary stakeholder engagement and coordination across all activities to provide alignment of global and regional strategies.

We take our clients on the RWE journey from initial evidence gap analysis and protocol design through study implementation and evidence dissemination, with the aim to establish and communicate the real-world value of their products.

1Evidence gap analysisWhere the value story needs proof

2Protocol designStudy, framework and data sources

3Study implementationSites, recruitment, data collection

4Evidence disseminationManuscripts, abstracts, posters

ResultReal-world value communicatedTo payers, HTAs and clinicians

Real-World Data (RWD) Analysis

Retrospective RWE studies utilize and analyze RWD collected from routine clinical practice or administrative sources to evaluate treatment outcomes, healthcare utilization patterns, and patient characteristics. In today’s world, harnessing the power of RWD has proved to be highly valuable in driving informed healthcare decisions, particularly in the setting of rare disease approvals and the support of expanded indications.

CCHO leverages a diverse range of RWD sources, including:

Electronic health records (EHRs)

Insurance billing and claims databases

Administrative and hospital databases

Established drug or disease registries

Patient-reported outcomes (PROs) and health surveys

Wearable devices and mobile health apps

Real-World Evidence (RWE) Generation

Our RWE generation services are designed to deliver robust insights into the effectiveness, safety, and value of healthcare products in real-world settings. CCHO guides you through every step of your RWE journey, starting by understanding your needs and objectives and designing the optimal study, to developing the protocol, establishing the analytical framework, identifying data sources, managing sites, patient recruitment, and data collection, and supporting your communications needs by developing manuscripts, abstracts, and posters.

We conduct various types of studies including:

Prospective drug / disease registries
Burden of illness
Patient-reported outcomes (PROs)
Treatment and population trends
Cost and healthcare resource utilization (HCRU) analysis

Evidence Synthesis and Evaluation

Systematic and targeted literature review
Network meta-analysis

Every project deserves a white-gloved bespoke approach.

Tell us about your objectives and we will design the study, strategy or programme around them.

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